ID: ALA5251882
Type: Functional
Description: Invivo PROTAC activity at VHL/SOS1 in human ASPC1 cells harboring KRAS G12D mutant xenografted BALB/c nude mouse assessed as induction of SOS1 degradation administered intraperitoneally once daily for 3 weeks by immunohistochemistry analysis
Organism: Mus musculus
Strain: BALB/c
Cell type: ASPC1
Bioactivity
Activity Types for Assay ALA5251882
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
1028.26 |