Assay Report Card

Basic Information

ID: ALA5251882

Type: Functional

Description: Invivo PROTAC activity at VHL/SOS1 in human ASPC1 cells harboring KRAS G12D mutant xenografted BALB/c nude mouse assessed as induction of SOS1 degradation administered intraperitoneally once daily for 3 weeks by immunohistochemistry analysis

Organism: Mus musculus

Strain: BALB/c

Cell type: ASPC1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1028.26