Basic Information
ID: ALA5251883
Type: Functional
Description: Invivo PROTAC activity at VHL/SOS1 in human ASPC1 cells harboring KRAS G12D mutant xenografted BALB/c nude mouse assessed as decrease in phosphorylated ERK expression at 10 to 20 mg/kg, ip administered once daily for 3 weeks by immunohistochemistry analysis
Organism: Mus musculus
Strain: BALB/c
Cell type: ASPC1
Activity Charts
Bioactivity
Activity Types for Assay ALA5251883
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1028.26 |