Assay Report Card

Basic Information

ID: ALA5251884

Type: Functional

Description: Invivo induction of SOS1 degradation in human ASPC1 cells harboring KRAS G12D mutant xenografted BALB/c nude mouse assessed as decrease in SOS1 level at 50 mg/kg, ip administered twice daily for 3 weeks by Immunoblot analysis

Organism: Mus musculus

Strain: BALB/c

Cell type: ASPC1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
462.474.894.89