Basic Information
ID: ALA5251889
Type: Functional
Description: Invivo PROTAC activity at VHL/SOS1 in human SW620 cells harboring KRAS G12V mutant xenografted BALB/c nude mouse assessed as decrease in phosphorylated ERK expression at 10 to 20 mg/kg, ip administered once daily for 2 weeks by Immunoblot analysis
Organism: Mus musculus
Strain: BALB/c
Cell type: SW-620
Activity Charts
Bioactivity
Activity Types for Assay ALA5251889
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1028.26 |