Basic Information
ID: ALA5251894
Type: Functional
Description: Invivo induction of SOS1 degradation in human SW620 cells harboring KRAS G12V mutant xenografted BALB/c nude mouse assessed as decrease in SOS1 level in tumor at 50 mg/kg, ip administered twice daily for 2 weeks by immunohistochemistry analysis
Organism: Mus musculus
Strain: BALB/c
Cell type: SW-620
Activity Charts
Bioactivity
Activity Types for Assay ALA5251894
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.47 | 4.89 | 4.89 |