Basic Information
ID: ALA5251895
Type: Functional
Description: Invivo Inhibition of ERK in human SW620 cells harboring KRAS G12V mutant xenografted BALB/c nude mouse assessed as inhibition of ERK phosphorylation in tumor at 50 mg/kg, ip administered twice daily for 2 weeks by immunohistochemistry analysis
Format: BAO_0000218
Organism: Mus musculus
Strain: BALB/c
Cell type: SW-620
Target: Unchecked(ALA612545)
Document: ALA5247656
Invivo Inhibition of ERK in human SW620 cells harboring KRAS G12V mutant xenografted BALB/c nude mouse assessed as inhibition of ERK phosphorylation in tumor at 50 mg/kg, ip administered twice daily for 2 weeks by immunohistochemistry analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5251895
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.47 | 4.89 | 4.89 |