ID: ALA5251897
Type: ADME
Description: Inhibition of CYP2C19 in pooled human liver microsomes using S-mephenytoin as substrate assessed as reduction in OH-S-mephenytoin metabolite formation by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Bioactivity
Activity Types for Assay ALA5251897
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
453.54 | 2.76 | 2.76 |