Basic Information
ID: ALA5251899
Type: Binding
Description: Inhibition of N-terminal His-tagged recombinant human BTK (393 to 659 residues) expressed in baculovirus infected Sf9 cells using Biotin-AVLESEEELYSSARQ-NH2 as substrate preincubated for 1 hrs followed by substrate addition in presence of ATP at Km concentration and measured after 1 hrs by TR-FRET assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA5251899
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 506.01 | 4.88 | 4.88 |
| 501.59 | 4.23 | 4.23 |
| 483.57 | 4.06 | 4.06 |
| 507.54 | 4.50 | 4.50 |
| 471.56 | 4.22 | 4.22 |
| 471.56 | 4.22 | 4.22 |
| 421.55 | 3.36 | 3.36 |
| 482.80 | 4.39 | 4.39 |
| 453.54 | 2.76 | 2.76 |
| 531.61 | 4.24 | 4.24 |
| 479.61 | 3.96 | 3.96 |
| 479.58 | 3.32 | 3.32 |
| 479.58 | 3.11 | 3.11 |
| 465.55 | 2.76 | 2.76 |
| 467.57 | 3.01 | 3.01 |
| 462.55 | 2.93 | 2.93 |
| 493.61 | 3.50 | 3.50 |
| 481.60 | 3.40 | 3.40 |
| 522.83 | 3.85 | 3.85 |
| 487.56 | 4.07 | 4.07 |
| 507.64 | 4.11 | 4.11 |
| 465.58 | 3.65 | 3.65 |
| 487.56 | 3.93 | 3.93 |
| 518.41 | 3.21 | 3.21 |
| 518.41 | 3.21 | 3.21 |
| 453.54 | 2.76 | 2.76 |
| 481.60 | 3.57 | 3.57 |
| 469.54 | 2.46 | 2.46 |
| 453.54 | 2.76 | 2.76 |
| 461.52 | 3.50 | 3.50 |
| 479.58 | 3.15 | 3.15 |
| 527.25 | 4.50 | 4.50 |
| 465.55 | 2.59 | 2.59 |
| 518.41 | 3.21 | 3.21 |
| 536.86 | 4.24 | 4.24 |
| 449.51 | 3.19 | 3.19 |
| 479.58 | 3.32 | 3.32 |
| 473.96 | 3.10 | 3.10 |
| 479.58 | 3.32 | 3.32 |