Basic Information
ID: ALA5251930
Type: Binding
Description: Selectivity ratio of IC50 for inhibition of EGFR autophosphorylation at Tyr1068 residue in EGFR-amplified human A-431 cells to IC50 for inhibition of BTK phosphorylation at Tyr 223 residue in human Ramos cells
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5251930
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.51 | 4.22 | 4.22 |
| 465.52 | 3.31 | 3.31 |
| 471.56 | 4.22 | 4.22 |
| 454.49 | 2.75 | 2.75 |
| 429.52 | 4.35 | 4.35 |
| 370.43 | 2.13 | 2.13 |
| 427.50 | 4.53 | 4.53 |
| 455.52 | 3.91 | 3.91 |
| 453.54 | 2.76 | 2.76 |
| 479.58 | 3.32 | 3.32 |