Assay Report Card

Basic Information

ID: ALA5251961

Type: ADME

Description: Inhibition of CYP2D6 in pooled human liver microsomes using dextromethorphan as substrate assessed as reduction in dextrophan metabolite formation by LC-MS/MS analysis

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
453.542.762.76