Basic Information
ID: ALA5251962
Type: ADME
Description: Inhibition of CYP3A4 in pooled human liver microsomes using midazolam as substrate assessed as reduction in OH-midazolam metabolite formation by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5251962
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 453.54 | 2.76 | 2.76 |