Assay Report Card

Basic Information

ID: ALA5252073

Type: ADME

Description: Substrate activity at P-glycoprotein in human Caco-2 cells assessed as efflux ratio of permeability across basolateral to apical side over apical to basolateral side at 3 uM incubated for 2 hrs by LC-MS/MS analysis

Organism: Homo sapiens

Cell type: Caco-2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
434.454.284.28
414.473.273.27
378.442.482.48
400.442.882.88