Basic Information
ID: ALA5252094
Type: Binding
Description: Activation of cGAMP-STING signaling pathway in human THP-1 cells assessed as increase in ISRE activation by measuring luciferase activation at 5 uM in presence of 1 ug/ml cGAMP by luciferase reporter gene assay relative to control
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA5252094
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 792.70 | 4.63 | 4.63 |
| 766.66 | 4.07 | 4.07 |
| 810.71 | 4.44 | 4.44 |
| 868.75 | 4.96 | 4.96 |
| 868.75 | 4.96 | 4.96 |
| 1013.96 | ||
| 895.78 | 3.12 | 3.12 |
| 967.84 | 3.06 | 3.06 |
| 866.78 | 4.99 | 4.99 |
| 842.76 | 5.64 | 5.64 |
| 882.78 | 5.35 | 5.35 |
| 882.78 | 5.35 | 5.35 |
| 840.74 | 4.06 | 4.06 |