Basic Information
ID: ALA5252387
Type: Toxicity
Description: Inhibition of human Nav1.1/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput electrophysiology system analysis
Organism: Homo sapiens
Cell type: HEK293-A
Activity Charts
Bioactivity
Activity Types for Assay ALA5252387
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.59 | 3.98 | 3.98 |
| 543.49 | 5.55 | 5.55 |
| 389.86 | 3.21 | 3.21 |
| 362.84 | 3.28 | 3.28 |
| 396.39 | 3.65 | 3.65 |
| 346.38 | 2.77 | 2.77 |
| 328.39 | 2.63 | 2.63 |
| 329.38 | 2.02 | 2.02 |
| 355.42 | 2.56 | 2.56 |
| 358.42 | 2.64 | 2.64 |
| 414.38 | 3.79 | 3.79 |
| 373.41 | 2.70 | 2.70 |
| 346.38 | 2.77 | 2.77 |
| 346.38 | 2.77 | 2.77 |
| 362.84 | 3.28 | 3.28 |
| 441.41 | 3.71 | 3.71 |
| 342.42 | 2.94 | 2.94 |
| 419.26 | 3.89 | 3.89 |
| 423.42 | 3.57 | 3.57 |
| 372.42 | 3.30 | 3.30 |
| 423.42 | 3.57 | 3.57 |
| 364.37 | 2.91 | 2.91 |