Basic Information
ID: ALA5252492
Type: Binding
Description: Inhibition of JAK1/TYK2 in human M07E cells assessed as reduction of IFN alpha stimulated STAT phosphorylation preincubated for 30 mins followed by IFN alpha stimulation for 15 mins by flow cytometry method
Organism: Homo sapiens
Cell type: M07E
Activity Charts
Bioactivity
Activity Types for Assay ALA5252492
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 306.37 | 3.47 | 3.47 |
| 310.36 | 1.30 | 1.30 |
| 355.79 | 3.42 | 3.42 |
| 369.81 | 3.72 | 3.72 |
| 353.81 | 4.02 | 4.02 |
| 355.79 | 3.42 | 3.42 |
| 427.85 | 4.25 | 4.25 |