Basic Information
ID: ALA5252493
Type: Binding
Description: Inhibition of JAK1/JAK3 in human blood assessed as reduction of IL-2 stimulated STAT phosphorylation preincubated for 30 mins followed by IL-2 stimulation for 15 mins by flow cytometry method
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA5252493
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 306.37 | 3.47 | 3.47 |
| 310.36 | 1.30 | 1.30 |
| 355.79 | 3.42 | 3.42 |
| 369.81 | 3.72 | 3.72 |
| 353.81 | 4.02 | 4.02 |
| 355.79 | 3.42 | 3.42 |
| 427.85 | 4.25 | 4.25 |