Assay Report Card

Basic Information

ID: ALA5252991

Type: Binding

Description: Binding affinity to wild-type HIV1 protease expressed in Escherichia coli BL21(DE3) assessed as inhibition constant using (2-aminobenzoyl)Thr-Ile-Nle-(p-nitro)Phe-Gln-Arg peptide as substrate preincubated for 15 mins followed by substrate addition by fluorimeter analysis

Organism: Human immunodeficiency virus 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
728.804.404.40
672.692.322.32