Basic Information
ID: ALA5253359
Type: Functional
Description: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 25618 expressing pATB45luc infected in PMA-stimulated human THP-1 cells assessed as inhibition of intracellular bacterial growth incubated for 4 days by BrightGlo luciferase assay
Organism: Mycobacterium tuberculosis
Strain: H37Rv ATCC 25618
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA5253359
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 350.42 | 4.19 | 4.19 |
| 352.39 | 3.58 | 3.58 |
| 352.39 | 3.58 | 3.58 |
| 356.81 | 4.22 | 4.22 |
| 368.41 | 4.33 | 4.33 |
| 334.38 | 4.58 | 4.58 |
| 319.36 | 4.01 | 4.01 |
| 358.34 | 3.85 | 3.85 |
| 364.45 | 4.21 | 4.21 |
| 391.25 | 4.88 | 4.88 |
| 366.42 | 3.89 | 3.89 |