Basic Information
ID: ALA5253740
Type: Binding
Description: Inhibition of P32-[alpha-GTP] cap radiolabelled RNA binding to recombinant eIF4E (unknown origin) assessed as decrease in cross linked RNA-eIF4E complex formation preincubated with UV radiation for 30 mins followed by RNase addition and measured after 30 mins by SDS-PAGE based autoradiographic analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5253740
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.26 | -3.14 | -3.14 |
| 538.22 | -2.91 | -2.91 |
| 581.65 | 0.27 | 0.27 |
| 325.40 | 2.22 | 2.22 |
| 366.23 | 3.54 | 3.54 |
| 557.57 | -1.06 | -1.06 |
| 393.34 | -3.84 | -3.84 |
| 469.43 | -2.32 | -2.32 |
| 356.41 | 2.90 | 2.90 |
| 483.47 | -2.87 | -2.87 |
| 511.52 | -1.20 | -1.20 |
| 420.56 | 4.07 | 4.07 |
| 407.37 | -4.38 | -4.38 |
| 499.46 | -2.32 | -2.32 |
| 503.88 | -1.67 | -1.67 |
| 325.40 | 2.22 | 2.22 |
| 483.46 | -2.02 | -2.02 |
| 505.46 | -1.30 | -1.30 |
| 423.54 | 3.79 | 3.79 |
| 537.43 | -1.31 | -1.31 |
| 481.47 | -2.57 | -2.57 |
| 487.42 | -2.19 | -2.19 |
| 336.83 | 4.22 | 4.22 |