Basic Information
ID: ALA5253920
Type: Binding
Description: Binding affinity to colchicine binding site of beta-tubulin in human HT-29 cells assessed as inhibition of beta-tubulin-EBI adduct formation at 10 uM pretreated for 2 hrs followed by EBI addition and measured after 1.5 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: HT-29
Activity Charts
Bioactivity
Activity Types for Assay ALA5253920
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 399.44 | 2.87 | 2.87 |
| 375.45 | 2.88 | 2.88 |