Basic Information
ID: ALA5254704
Type: Binding
Description: Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current amplitude at -80 mV holding potential in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay
Organism: Rattus norvegicus
Cell type: Oocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA5254704
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.75 | 3.15 | 3.15 |
| 291.31 | 2.83 | 2.83 |
| 305.34 | 3.14 | 3.14 |
| 315.33 | 2.81 | 2.81 |