Basic Information
ID: ALA5255943
Type: Binding
Description: Positive allosteric modulation of GluN1/GluN2B receptor (unknown origin) stably expressed in HEK293 cells assessed as glutamate/glycine induced increase in intracellular calcium level at 10 uM incubated for 30 mins followed by addition of glutamate/glycine by Ca2+ influx assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Glutamate NMDA receptor; GRIN1/GRIN2B(ALA1907603)
Document: ALA5252626
Positive allosteric modulation of GluN1/GluN2B receptor (unknown origin) stably expressed in HEK293 cells assessed as glutamate/glycine induced increase in intracellular calcium level at 10 uM incubated for 30 mins followed by addition of glutamate/glycine by Ca2+ influx assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5255943
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 294.31 | 2.79 | 2.79 |
| 355.78 | 3.39 | 3.39 |
| 432.10 | 4.62 | 4.62 |
| 328.75 | 3.44 | 3.44 |