Basic Information
ID: ALA5256457
Type: Binding
Description: PROTAC activity at CRBN/H-PGDS in human KU812 cells assessed as induction of H-PGDS degradation by measuring decrease in H-PGDS protein expression incubated for 24 hrs by western blot analysis
Organism: Homo sapiens
Cell type: KU812 cell line
Activity Charts
Bioactivity
Activity Types for Assay ALA5256457
DC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 742.79 | 3.49 | 3.49 |
| 763.86 | 1.98 | 1.98 |
| 742.79 | 3.49 | 3.49 |
| 763.86 | 1.98 | 1.98 |
| 760.78 | 3.63 | 3.63 |
| 730.83 | 4.04 | 4.04 |