Basic Information
ID: ALA5256718
Type: ADME
Description: Metabolic stability in rat liver microsomes assessed as intrinsic clearance preincubation with compound followed by NADPH addition and measured after 45 mins by LC-MS/MS analysis
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5256718
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 391.33 | 2.70 | 2.70 |
| 372.35 | 3.16 | 3.16 |
| 376.31 | 3.26 | 3.26 |
| 404.37 | 3.69 | 3.69 |
| 404.37 | 3.64 | 3.64 |
| 386.38 | 3.53 | 3.53 |
| 424.79 | 3.96 | 3.96 |
| 404.37 | 3.61 | 3.61 |
| 390.34 | 3.30 | 3.30 |
| 404.37 | 3.61 | 3.61 |
| 390.34 | 3.30 | 3.30 |
| 371.36 | 4.40 | 4.40 |
| 390.34 | 3.30 | 3.30 |
| 402.38 | 3.19 | 3.19 |
| 372.35 | 3.22 | 3.22 |
| 389.35 | 3.91 | 3.91 |
| 390.34 | 3.30 | 3.30 |