Allosteric agonist activity at mGluR7 (unknown origin) assessed as reduction in forskolin-induced cAMP production by measuring fold change in EC50 pre...

Basic Information

ID: ALA5256807

Type: Binding

Description: Allosteric agonist activity at mGluR7 (unknown origin) assessed as reduction in forskolin-induced cAMP production by measuring fold change in EC50 preincubated for 15 mins in the presence of LY341495 followed by forskolin stimulation and measured after 5 hrs by luminescence based steady glo assay

Format: BAO_0000019

Organism: Homo sapiens

Target:  Metabotropic glutamate receptor 7(ALA3777)

Document:  ALA5252666

Allosteric agonist activity at mGluR7 (unknown origin) assessed as reduction in forskolin-induced cAMP production by measuring fold change in EC50 preincubated for 15 mins in the presence of LY341495 followed by forskolin stimulation and measured after 5 hrs by luminescence based steady glo assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
392.555.745.74
377.442.592.59