Basic Information
ID: ALA5256816
Type: Binding
Description: Inhibition of human CHIT1 using 4-methylumbelliferyl-beta-D-N,N',N''-triacetylchitotriose as substrate assessed as substrate hydrolysis by measuring inhibition constant preincubated with compound for 20 mins and measured immediately after substrate addition by fluorescence based assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5256816
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 386.37 | -1.74 | -1.74 |
| 516.69 | 3.47 | 3.47 |
| 582.73 | 4.18 | 4.18 |
| 578.76 | 4.35 | 4.35 |
| 599.18 | 4.70 | 4.70 |
| 599.18 | 4.70 | 4.70 |
| 648.73 | 4.94 | 4.94 |
| 460.58 | 1.91 | 1.91 |
| 488.64 | 2.69 | 2.69 |
| 502.66 | 3.08 | 3.08 |
| 530.72 | 3.81 | 3.81 |
| 459.64 | 3.50 | 3.50 |
| 532.76 | 3.63 | 3.63 |
| 564.74 | 4.04 | 4.04 |
| 578.76 | 4.35 | 4.35 |
| 582.73 | 4.18 | 4.18 |
| 438.62 | 2.67 | 2.67 |
| 578.76 | 4.35 | 4.35 |
| 546.72 | 2.83 | 2.83 |
| 488.64 | 2.69 | 2.69 |
| 582.73 | 4.18 | 4.18 |
| 594.76 | 4.05 | 4.05 |
| 582.73 | 4.18 | 4.18 |