Basic Information
ID: ALA5257504
Type: Functional
Description: Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell growth incubated for 48 hrs by propidium iodide staining based fluorometer assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H460
Target: NCI-H460(ALA396)
Document: ALA5257024
Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell growth incubated for 48 hrs by propidium iodide staining based fluorometer assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5257504
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.44 | 3.41 | 3.41 |
| 403.31 | 6.23 | 6.23 |
| 463.36 | 6.25 | 6.25 |
| 612.31 | 6.48 | 6.48 |
| 417.33 | 6.48 | 6.48 |
| 477.38 | 6.49 | 6.49 |
| 626.34 | 6.73 | 6.73 |
| 445.39 | 7.11 | 7.11 |
| 505.44 | 7.13 | 7.13 |
| 654.39 | 7.37 | 7.37 |
| 404.29 | 4.65 | 4.65 |
| 464.35 | 4.67 | 4.67 |
| 613.30 | 4.90 | 4.90 |
| 418.32 | 4.99 | 4.99 |
| 478.37 | 5.01 | 5.01 |
| 627.33 | 5.24 | 5.24 |
| 494.42 | 6.56 | 6.56 |
| 554.47 | 6.58 | 6.58 |
| 703.42 | 6.82 | 6.82 |
| 405.28 | 5.08 | 5.08 |
| 465.33 | 5.09 | 5.09 |
| 614.28 | 5.33 | 5.33 |
| 358.82 | 4.58 | 4.58 |
| 463.32 | 4.70 | 4.70 |
| 373.79 | 4.48 | 4.48 |
| 298.77 | 4.56 | 4.56 |
| 437.72 | 5.34 | 5.34 |
| 344.79 | 4.28 | 4.28 |
| 316.76 | 4.70 | 4.70 |
| 358.82 | 4.58 | 4.58 |
| 741.52 | 6.39 | 6.39 |
| 312.80 | 5.12 | 5.12 |
| 388.85 | 4.59 | 4.59 |
| 377.67 | 5.32 | 5.32 |
| 403.27 | 4.69 | 4.69 |
| 363.24 | 5.22 | 5.22 |
| 343.77 | 4.47 | 4.47 |
| 627.33 | 6.74 | 6.74 |
| 346.79 | 4.71 | 4.71 |
| 314.77 | 4.27 | 4.27 |
| 433.30 | 4.70 | 4.70 |
| 641.35 | 6.99 | 6.99 |
| 358.82 | 4.58 | 4.58 |
| 417.30 | 5.25 | 5.25 |
| 448.27 | 4.60 | 4.60 |
| 448.31 | 4.69 | 4.69 |
| 433.30 | 4.70 | 4.70 |
| 328.80 | 4.57 | 4.57 |
| 642.34 | 5.51 | 5.51 |
| 407.69 | 5.33 | 5.33 |
| 478.34 | 4.70 | 4.70 |
| 562.46 | 5.48 | 5.48 |
| 342.82 | 5.13 | 5.13 |
| 421.26 | 4.83 | 4.83 |
| 487.98 | 5.36 | 5.36 |
| 740.53 | 7.87 | 7.87 |
| 328.80 | 4.57 | 4.57 |
| 463.28 | 4.59 | 4.59 |
| 482.17 | 5.45 | 5.45 |
| 388.81 | 4.47 | 4.47 |
| 463.32 | 4.70 | 4.70 |
| 328.80 | 4.57 | 4.57 |
| 432.31 | 5.24 | 5.24 |
| 419.27 | 4.39 | 4.39 |
| 434.29 | 4.39 | 4.39 |
| 358.82 | 4.58 | 4.58 |
| 478.34 | 4.70 | 4.70 |
| 577.52 | 5.58 | 5.58 |
| 333.21 | 5.21 | 5.21 |
| 388.85 | 4.59 | 4.59 |