Basic Information
ID: ALA5257509
Type: Binding
Description: Inhibition of recombinant 6His-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) autophosphorylation expressed in baculovirus infected Sf9 insect cells preincubated for 10 mins followed by ATP and MgCl2 addition measured after 60 mins by DELFIA/time-resolved fluorometric analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Epidermal growth factor receptor erbB1(ALA203)
Document: ALA5257024
Inhibition of recombinant 6His-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) autophosphorylation expressed in baculovirus infected Sf9 insect cells preincubated for 10 mins followed by ATP and MgCl2 addition measured after 60 mins by DELFIA/time-resolved fluorometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5257509
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.44 | 3.41 | 3.41 |
| 741.52 | 6.39 | 6.39 |
| 641.35 | 6.99 | 6.99 |
| 448.31 | 4.69 | 4.69 |
| 642.34 | 5.51 | 5.51 |
| 478.34 | 4.70 | 4.70 |
| 463.28 | 4.59 | 4.59 |
| 388.81 | 4.47 | 4.47 |
| 432.31 | 5.24 | 5.24 |
| 434.29 | 4.39 | 4.39 |
| 478.34 | 4.70 | 4.70 |