Basic Information
ID: ALA5257510
Type: Binding
Description: Inhibition of full length mouse GST-tagged BRAF V600E mutant preincubated for 60 mins followed by addition of N-terminal His-tagged full length human MEK1 incubated for 25 mins in presence of ATP by ELISA assay
Format: BAO_0000019
Organism: Mus musculus
Target: Unchecked(ALA612545)
Document: ALA5257024
Inhibition of full length mouse GST-tagged BRAF V600E mutant preincubated for 60 mins followed by addition of N-terminal His-tagged full length human MEK1 incubated for 25 mins in presence of ATP by ELISA assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5257510
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.44 | 3.41 | 3.41 |
| 741.52 | 6.39 | 6.39 |
| 641.35 | 6.99 | 6.99 |
| 448.31 | 4.69 | 4.69 |
| 642.34 | 5.51 | 5.51 |
| 478.34 | 4.70 | 4.70 |
| 463.28 | 4.59 | 4.59 |
| 388.81 | 4.47 | 4.47 |
| 432.31 | 5.24 | 5.24 |
| 434.29 | 4.39 | 4.39 |
| 478.34 | 4.70 | 4.70 |