Basic Information
ID: ALA5257512
Type: Functional
Description: Reversal of multidrug resistance in mouse L5178Y cells transfected with human MDR1 assessed as reversal of rhodamine 123 accumulation by measuring fluorescence activity ratio at 50 ug/ml incubated for 30 mins by flow cytometry
Format: BAO_0000219
Organism: Mus musculus
Cell type: L5178Y
Target: L5178Y(ALA614720)
Document: ALA5257024
Reversal of multidrug resistance in mouse L5178Y cells transfected with human MDR1 assessed as reversal of rhodamine 123 accumulation by measuring fluorescence activity ratio at 50 ug/ml incubated for 30 mins by flow cytometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5257512
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 393.44 | 3.41 | 3.41 |
| 641.35 | 6.99 | 6.99 |
| 448.31 | 4.69 | 4.69 |
| 642.34 | 5.51 | 5.51 |
| 478.34 | 4.70 | 4.70 |
| 463.28 | 4.59 | 4.59 |
| 388.81 | 4.47 | 4.47 |
| 432.31 | 5.24 | 5.24 |
| 434.29 | 4.39 | 4.39 |
| 478.34 | 4.70 | 4.70 |