Basic Information
ID: ALA5258231
Type: Binding
Description: Positive allosteric modulator activity at rat mGlu5 in human HEK cells assessed as increase in calcium flux preincubated for 2.5 mins followed by gluatamate addition by Fluo-4 AM dye based calcium mobilization assay
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: HEK
Target: Metabotropic glutamate receptor 5(ALA2564)
Document: ALA5257040
Positive allosteric modulator activity at rat mGlu5 in human HEK cells assessed as increase in calcium flux preincubated for 2.5 mins followed by gluatamate addition by Fluo-4 AM dye based calcium mobilization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5258231
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 329.29 | 4.27 | 4.27 |