Positive allosteric modulator activity at rat mGlu1 in human HEK cells assessed assessed as increase in calcium flux preincubated for 2.5 mins followe...

Basic Information

ID: ALA5258234

Type: Binding

Description: Positive allosteric modulator activity at rat mGlu1 in human HEK cells assessed assessed as increase in calcium flux preincubated for 2.5 mins followed by gluatamate addition by Fluo-4 AM dye based calcium mobilization assay

Format: BAO_0000219

Organism: Rattus norvegicus

Cell type: HEK

Target:  Metabotropic glutamate receptor 1(ALA4477)

Document:  ALA5257040

Positive allosteric modulator activity at rat mGlu1 in human HEK cells assessed assessed as increase in calcium flux preincubated for 2.5 mins followed by gluatamate addition by Fluo-4 AM dye based calcium mobilization assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
329.294.274.27