Positive allosteric modulator activity at rat mGlu4 in human HEK cells co-expressing GRIK assessed as maximum increase in by thallium flux preincubate...

Basic Information

ID: ALA5258235

Type: Binding

Description: Positive allosteric modulator activity at rat mGlu4 in human HEK cells co-expressing GRIK assessed as maximum increase in by thallium flux preincubated for 2.5 mins followed by gluatamate addition and measured for 2 mins by thallium flux assay

Format: BAO_0000219

Organism: Rattus norvegicus

Cell type: HEK

Target:  Metabotropic glutamate receptor 4(ALA2787)

Document:  ALA5257040

Positive allosteric modulator activity at rat mGlu4 in human HEK cells co-expressing GRIK assessed as maximum increase in by thallium flux preincubated for 2.5 mins followed by gluatamate addition and measured for 2 mins by thallium flux assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
329.294.274.27