Basic Information
ID: ALA5258237
Type: Binding
Description: Positive allosteric modulator activity at human mGlu4 in Chinese hamster CHO cells co-expressing Gqi5 assessed as maximum increase in calcium flux preincubated for 2.5 mins followed by gluatamate addition and measured for 2 mins by Fluo-4 AM dye based calcium mobilization assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Metabotropic glutamate receptor 4(ALA2736)
Document: ALA5257040
Positive allosteric modulator activity at human mGlu4 in Chinese hamster CHO cells co-expressing Gqi5 assessed as maximum increase in calcium flux preincubated for 2.5 mins followed by gluatamate addition and measured for 2 mins by Fluo-4 AM dye based calcium mobilization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5258237
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 329.29 | 4.27 | 4.27 |