Basic Information
ID: ALA5258344
Type: Binding
Description: Inhibition of recombinant N-terminal His-Avi-tag human FGFR3 (447 to 761 residues) expressed in Sf9 infected baculovirus expression system using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by substrate addition and measured after 1 hr in presence of ATP by HTRF assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA5258344
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.57 | 2.44 | 2.44 |
| 408.47 | 1.38 | 1.38 |
| 351.41 | 1.73 | 1.73 |
| 437.51 | 0.36 | 0.36 |
| 351.41 | 1.82 | 1.82 |
| 340.39 | 0.81 | 0.81 |
| 365.44 | 2.38 | 2.38 |
| 312.34 | 0.03 | 0.03 |
| 378.44 | 1.75 | 1.75 |
| 369.40 | 1.67 | 1.67 |
| 365.44 | 2.11 | 2.11 |
| 382.43 | 0.67 | 0.67 |
| 326.36 | 0.42 | 0.42 |
| 326.36 | 0.42 | 0.42 |
| 364.41 | 1.36 | 1.36 |
| 378.44 | 1.75 | 1.75 |
| 422.49 | 1.50 | 1.50 |
| 337.39 | 1.34 | 1.34 |