Basic Information
ID: ALA5259065
Type: Binding
Description: Partial agonist activity at N-terminal FLAG tagged/C-terminal NanoLuc tagged human muscarinic M1 receptor expressed in HEK293T cells using furimazine as substrate assessed as receptor activation by measuring maximum efficacy preincubated with substrate for 1 min followed by compound addition and measured for 6 mins 27 sec by NanoBRET assay relative to control
Organism: Homo sapiens
Cell type: HEK293T
Activity Charts
Bioactivity
Activity Types for Assay ALA5259065
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 208.26 | 1.16 | 1.16 |
| 180.21 | 0.53 | 0.53 |
| 208.26 | 1.16 | 1.16 |
| 166.18 | 0.52 | 0.52 |
| 790.68 | 5.95 | 5.95 |
| 692.85 | 5.17 | 5.17 |
| 762.63 | 5.17 | 5.17 |
| 650.77 | 4.52 | 4.52 |