Basic Information
ID: ALA5259462
Type: Binding
Description: Inhibition of recombinant human GSK3beta (636 to 661 residues) assessed as reduction in human muscle glycogen synthase type 1 fragment phosphorylation using YRRAAVPPSPSLSRHSSPHQ(pS)EDE as substrate in presence of ATP incubated for 60 mins by ADP-Glo kinase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5259462
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 237.26 | 2.88 | 2.88 |
| 371.22 | 4.05 | 4.05 |
| 256.22 | 2.68 | 2.68 |
| 236.27 | 2.46 | 2.46 |
| 238.29 | 2.55 | 2.55 |
| 400.43 | 3.66 | 3.66 |
| 267.24 | 2.48 | 2.48 |
| 356.38 | 4.14 | 4.14 |
| 283.29 | 1.73 | 1.73 |
| 279.30 | 2.53 | 2.53 |
| 236.27 | 2.60 | 2.60 |
| 339.31 | 3.27 | 3.27 |
| 225.25 | 1.91 | 1.91 |
| 328.28 | 1.99 | 1.99 |
| 368.39 | 3.16 | 3.16 |
| 239.28 | 1.94 | 1.94 |
| 310.31 | 3.06 | 3.06 |
| 224.26 | 2.36 | 2.36 |
| 294.31 | 2.84 | 2.84 |
| 225.25 | 2.21 | 2.21 |