Basic Information
ID: ALA5259874
Type: Binding
Description: Inhibition of PI3Kalpha (unknown origin) using PIP2:PS as substrate preincubated for 1 hr followed by ATP and substate addition and measured after 1 hr by ADP-glo reagent based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5259874
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.42 | 2.42 | 2.42 |
| 375.43 | 2.77 | 2.77 |
| 465.56 | 4.32 | 4.32 |
| 361.41 | 2.30 | 2.30 |
| 493.45 | 3.92 | 3.92 |
| 369.43 | 0.73 | 0.73 |
| 391.48 | 3.06 | 3.06 |
| 361.41 | 2.30 | 2.30 |
| 363.38 | 0.97 | 0.97 |
| 349.39 | 2.03 | 2.03 |
| 348.37 | 1.39 | 1.39 |
| 477.45 | 4.04 | 4.04 |
| 390.45 | 2.06 | 2.06 |
| 361.41 | 2.30 | 2.30 |
| 350.42 | 2.35 | 2.35 |
| 350.38 | 1.33 | 1.33 |
| 487.54 | 2.43 | 2.43 |
| 361.41 | 2.30 | 2.30 |
| 347.38 | 1.99 | 1.99 |
| 431.50 | 1.76 | 1.76 |
| 339.40 | 1.06 | 1.06 |
| 373.42 | 2.38 | 2.38 |
| 367.45 | 1.88 | 1.88 |
| 389.46 | 3.12 | 3.12 |
| 347.38 | 1.99 | 1.99 |
| 350.42 | 2.35 | 2.35 |
| 362.39 | 1.58 | 1.58 |
| 376.42 | 2.04 | 2.04 |
| 361.41 | 2.04 | 2.04 |
| 383.45 | 1.12 | 1.12 |
| 341.42 | 1.35 | 1.35 |
| 394.48 | 1.03 | 1.03 |
| 347.38 | 1.99 | 1.99 |
| 449.49 | 1.90 | 1.90 |
| 361.41 | 2.30 | 2.30 |
| 364.45 | 2.74 | 2.74 |
| 365.44 | 1.88 | 1.88 |
| 284.32 | 1.42 | 1.42 |
| 361.41 | 2.30 | 2.30 |
| 347.38 | 1.99 | 1.99 |
| 355.40 | 0.25 | 0.25 |
| 348.37 | 1.39 | 1.39 |
| 401.47 | 2.63 | 2.63 |
| 346.39 | 2.45 | 2.45 |
| 346.39 | 2.60 | 2.60 |
| 314.35 | 1.05 | 1.05 |
| 395.51 | 2.66 | 2.66 |
| 405.42 | 1.35 | 1.35 |