Basic Information
ID: ALA5260328
Type: Binding
Description: Allosteric inhibition of recombinant human SHP2 using IRS1 peptide and DiFMUP as substrate incubated for 30 mins followed by DiFMUP addition and measured after 30 mins by fluorescence based microplate reader analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5260328
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 437.37 | 3.58 | 3.58 |
| 451.36 | 4.64 | 4.64 |
| 483.52 | 3.88 | 3.88 |
| 523.09 | 4.71 | 4.71 |
| 478.97 | 2.37 | 2.37 |
| 518.59 | 4.04 | 4.04 |
| 466.38 | 4.07 | 4.07 |
| 493.58 | 3.74 | 3.74 |
| 492.01 | 3.29 | 3.29 |
| 498.54 | 3.67 | 3.67 |
| 485.98 | 3.23 | 3.23 |
| 512.43 | 3.63 | 3.63 |
| 471.96 | 2.92 | 2.92 |
| 509.06 | 4.32 | 4.32 |
| 471.42 | 4.74 | 4.74 |
| 473.53 | 3.37 | 3.37 |
| 493.00 | 2.68 | 2.68 |
| 471.51 | 3.85 | 3.85 |
| 503.58 | 4.33 | 4.33 |
| 506.04 | 3.68 | 3.68 |
| 474.96 | 2.26 | 2.26 |
| 469.50 | 3.84 | 3.84 |
| 486.43 | 4.44 | 4.44 |
| 492.01 | 3.44 | 3.44 |
| 497.55 | 4.27 | 4.27 |
| 470.97 | 3.52 | 3.52 |
| 545.98 | 4.00 | 4.00 |
| 486.53 | 3.55 | 3.55 |
| 474.96 | 2.49 | 2.49 |
| 486.43 | 4.44 | 4.44 |
| 483.52 | 4.23 | 4.23 |
| 477.99 | 2.98 | 2.98 |
| 465.39 | 4.68 | 4.68 |
| 492.01 | 3.29 | 3.29 |
| 472.54 | 3.98 | 3.98 |
| 486.43 | 4.44 | 4.44 |
| 477.99 | 3.05 | 3.05 |