Basic Information
ID: ALA5260329
Type: Binding
Description: Inhibition of ERK phosphorylation in human KYSE520 cells incubated for 2 hrs by TR-FRET assay
Organism: Homo sapiens
Cell type: KYSE520
Activity Charts
Bioactivity
Activity Types for Assay ALA5260329
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 437.37 | 3.58 | 3.58 |
| 451.36 | 4.64 | 4.64 |
| 483.52 | 3.88 | 3.88 |
| 523.09 | 4.71 | 4.71 |
| 478.97 | 2.37 | 2.37 |
| 518.59 | 4.04 | 4.04 |
| 466.38 | 4.07 | 4.07 |
| 493.58 | 3.74 | 3.74 |
| 492.01 | 3.29 | 3.29 |
| 498.54 | 3.67 | 3.67 |
| 485.98 | 3.23 | 3.23 |
| 512.43 | 3.63 | 3.63 |
| 471.96 | 2.92 | 2.92 |
| 509.06 | 4.32 | 4.32 |
| 471.42 | 4.74 | 4.74 |
| 473.53 | 3.37 | 3.37 |
| 493.00 | 2.68 | 2.68 |
| 471.51 | 3.85 | 3.85 |
| 503.58 | 4.33 | 4.33 |
| 506.04 | 3.68 | 3.68 |
| 474.96 | 2.26 | 2.26 |
| 469.50 | 3.84 | 3.84 |
| 486.43 | 4.44 | 4.44 |
| 492.01 | 3.44 | 3.44 |
| 497.55 | 4.27 | 4.27 |
| 470.97 | 3.52 | 3.52 |
| 545.98 | 4.00 | 4.00 |
| 486.53 | 3.55 | 3.55 |
| 474.96 | 2.49 | 2.49 |
| 486.43 | 4.44 | 4.44 |
| 483.52 | 4.23 | 4.23 |
| 477.99 | 2.98 | 2.98 |
| 465.39 | 4.68 | 4.68 |
| 492.01 | 3.29 | 3.29 |
| 472.54 | 3.98 | 3.98 |
| 486.43 | 4.44 | 4.44 |
| 477.99 | 3.05 | 3.05 |