Basic Information
ID: ALA5260350
Type: Binding
Description: Inhibition of human N-terminal His6-tagged recombinant full-length PLK1 expressed in baculovirus infected Sf9 cells incubated for 15 mins followed by ATP addition by ADP Glo luminescent assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA5260350
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 618.83 | 4.27 | 4.27 |
| 500.61 | 2.89 | 2.89 |
| 537.63 | 3.08 | 3.08 |
| 474.57 | 2.24 | 2.24 |
| 528.66 | 3.82 | 3.82 |
| 509.44 | 5.28 | 5.28 |
| 481.48 | 3.91 | 3.91 |
| 568.73 | 4.76 | 4.76 |
| 518.62 | 2.35 | 2.35 |
| 511.63 | 4.22 | 4.22 |
| 540.67 | 3.98 | 3.98 |
| 571.09 | 4.34 | 4.34 |
| 551.65 | 4.33 | 4.33 |
| 553.67 | 3.38 | 3.38 |
| 527.67 | 4.87 | 4.87 |
| 561.65 | 3.56 | 3.56 |
| 540.67 | 3.98 | 3.98 |
| 566.67 | 3.70 | 3.70 |
| 470.58 | 3.73 | 3.73 |
| 550.67 | 4.00 | 4.00 |
| 542.69 | 4.21 | 4.21 |
| 502.62 | 3.11 | 3.11 |
| 620.64 | 4.59 | 4.59 |
| 460.54 | 2.23 | 2.23 |
| 466.37 | 5.21 | 5.21 |
| 550.67 | 4.00 | 4.00 |
| 513.65 | 4.12 | 4.12 |
| 539.68 | 5.04 | 5.04 |
| 485.59 | 3.52 | 3.52 |
| 526.65 | 3.59 | 3.59 |
| 583.50 | 5.34 | 5.34 |
| 499.62 | 3.86 | 3.86 |
| 427.51 | 3.20 | 3.20 |
| 539.62 | 5.17 | 5.17 |
| 540.67 | 3.98 | 3.98 |
| 537.62 | 3.93 | 3.93 |
| 511.63 | 4.22 | 4.22 |
| 502.62 | 3.28 | 3.28 |
| 565.68 | 4.76 | 4.76 |
| 528.66 | 3.50 | 3.50 |
| 570.70 | 3.34 | 3.34 |
| 554.63 | 3.83 | 3.83 |
| 501.59 | 3.27 | 3.27 |
| 536.64 | 3.69 | 3.69 |
| 526.65 | 3.59 | 3.59 |
| 452.35 | 4.99 | 4.99 |
| 526.65 | 3.59 | 3.59 |
| 565.68 | 4.67 | 4.67 |
| 497.60 | 4.17 | 4.17 |