Basic Information
ID: ALA5260380
Type: Binding
Description: Binding affinity to CRBN/IRAK4 in human PBMC cells assessed as inhibition of R848-stimulated IL-6 production by measuring maximal efficacy incubated for 24 hrs by MSD analysis relative to control
Organism: Homo sapiens
Cell type: PBMC
Activity Charts
Bioactivity
Activity Types for Assay ALA5260380
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 866.95 | 4.17 | 4.17 |
| 787.88 | 3.51 | 3.51 |
| 780.84 | 4.29 | 4.29 |
| 877.95 | 3.11 | 3.11 |
| 854.03 | 3.75 | 3.75 |
| 787.88 | 3.51 | 3.51 |
| 781.82 | 3.32 | 3.32 |
| 854.03 | 3.75 | 3.75 |
| 770.89 | 4.43 | 4.43 |
| 843.96 | 3.07 | 3.07 |