Basic Information
ID: ALA5260383
Type: Binding
Description: Inhibition of porcine PDHc E1-subunit assessed as DCPIP reduction at 250 uM preincubated for 30 mins followed by pyruvate addition using 50 uM ThDP as substrate by microplate reader analysis
Organism: Sus scrofa
Activity Charts
Bioactivity
Activity Types for Assay ALA5260383
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.30 | 0.97 | 0.97 |
| 234.26 | -0.46 | -0.46 |
| 262.32 | 0.32 | 0.32 |
| 248.29 | -0.07 | -0.07 |
| 363.38 | 1.28 | 1.28 |
| 391.44 | 1.52 | 1.52 |
| 474.40 | 2.48 | 2.48 |
| 367.41 | 0.99 | 0.99 |
| 393.40 | 0.77 | 0.77 |
| 380.46 | 1.94 | 1.94 |
| 291.31 | -0.16 | -0.16 |
| 405.47 | 1.91 | 1.91 |
| 419.49 | 2.30 | 2.30 |
| 367.41 | 0.99 | 0.99 |
| 379.40 | 1.65 | 1.65 |
| 395.47 | 1.77 | 1.77 |
| 379.37 | 0.38 | 0.38 |
| 473.42 | 2.05 | 2.05 |
| 277.29 | -0.55 | -0.55 |
| 375.44 | 1.90 | 1.90 |
| 365.34 | -0.01 | -0.01 |
| 381.44 | 1.38 | 1.38 |
| 366.43 | 1.55 | 1.55 |
| 407.46 | 2.43 | 2.43 |
| 395.47 | 1.77 | 1.77 |
| 389.47 | 2.29 | 2.29 |
| 361.41 | 1.51 | 1.51 |
| 352.40 | 1.16 | 1.16 |
| 381.44 | 1.38 | 1.38 |
| 305.34 | 0.23 | 0.23 |
| 362.40 | 0.85 | 0.85 |
| 393.43 | 2.04 | 2.04 |