Basic Information
ID: ALA5260384
Type: Binding
Description: Inhibition of Escherichia coli OGDHc E1 subunit assessed as DCPIP reduction at 250 uM preincubated for 60 mins followed by pyruvate addition using 50 uM ThDP as substrate by microplate reader analysis
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA5260384
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.30 | 0.97 | 0.97 |
| 234.26 | -0.46 | -0.46 |
| 262.32 | 0.32 | 0.32 |
| 248.29 | -0.07 | -0.07 |
| 363.38 | 1.28 | 1.28 |
| 391.44 | 1.52 | 1.52 |
| 474.40 | 2.48 | 2.48 |
| 367.41 | 0.99 | 0.99 |
| 393.40 | 0.77 | 0.77 |
| 380.46 | 1.94 | 1.94 |
| 291.31 | -0.16 | -0.16 |
| 405.47 | 1.91 | 1.91 |
| 419.49 | 2.30 | 2.30 |
| 367.41 | 0.99 | 0.99 |
| 379.40 | 1.65 | 1.65 |
| 395.47 | 1.77 | 1.77 |
| 379.37 | 0.38 | 0.38 |
| 473.42 | 2.05 | 2.05 |
| 277.29 | -0.55 | -0.55 |
| 375.44 | 1.90 | 1.90 |
| 365.34 | -0.01 | -0.01 |
| 381.44 | 1.38 | 1.38 |
| 366.43 | 1.55 | 1.55 |
| 407.46 | 2.43 | 2.43 |
| 395.47 | 1.77 | 1.77 |
| 389.47 | 2.29 | 2.29 |
| 361.41 | 1.51 | 1.51 |
| 352.40 | 1.16 | 1.16 |
| 381.44 | 1.38 | 1.38 |
| 305.34 | 0.23 | 0.23 |
| 362.40 | 0.85 | 0.85 |
| 393.43 | 2.04 | 2.04 |