Basic Information
ID: ALA5260405
Type: Toxicity
Description: Selectivity index, ratio of IC50 for cytotoxicity against human HFF cells to antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum 3D7 infected in human erythrocyte assessed as inhibition of parasite proliferation in thiamine free medium
Format: BAO_0000219
Target: ADMET(ALA612558)
Document: ALA5257137
Selectivity index, ratio of IC50 for cytotoxicity against human HFF cells to antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum 3D7 infected in human erythrocyte assessed as inhibition of parasite proliferation in thiamine free medium: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5260405
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.35 | 0.73 | 0.73 |
| 391.44 | 1.52 | 1.52 |
| 291.31 | -0.16 | -0.16 |
| 405.47 | 1.91 | 1.91 |
| 419.49 | 2.30 | 2.30 |
| 379.40 | 1.65 | 1.65 |
| 407.46 | 2.43 | 2.43 |
| 305.34 | 0.23 | 0.23 |
| 393.43 | 2.04 | 2.04 |