Basic Information
ID: ALA5260410
Type: Binding
Description: Inhibition of Escherichia coli OGDHc E1 subunit assessed as DCPIP reduction at 250 uM preincubated for 60 mins followed by pyruvate addition using 125 uM ThDP as substrate by microplate reader analysis
Format: BAO_0000019
Organism: Escherichia coli
Target: Unchecked(ALA612545)
Document: ALA5257137
Inhibition of Escherichia coli OGDHc E1 subunit assessed as DCPIP reduction at 250 uM preincubated for 60 mins followed by pyruvate addition using 125 uM ThDP as substrate by microplate reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5260410
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.30 | 0.97 | 0.97 |
| 391.44 | 1.52 | 1.52 |
| 291.31 | -0.16 | -0.16 |
| 405.47 | 1.91 | 1.91 |
| 419.49 | 2.30 | 2.30 |
| 379.40 | 1.65 | 1.65 |
| 375.44 | 1.90 | 1.90 |
| 407.46 | 2.43 | 2.43 |
| 389.47 | 2.29 | 2.29 |
| 361.41 | 1.51 | 1.51 |
| 305.34 | 0.23 | 0.23 |
| 393.43 | 2.04 | 2.04 |