Basic Information
ID: ALA5260433
Type: Binding
Description: Inhibition of PARP1 (unknown origin) with prodrug pretreated for 2 hrs in human liver lysosome lysate using biotinylated NAD+ and activated DNA template as substrate at 0.5 uM by colorimetric assay relative to control
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Lysosome
Activity Charts
Bioactivity
Activity Types for Assay ALA5260433
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 244.30 | 1.26 | 1.26 |
| 564.64 | 4.16 | 4.16 |
| 565.63 | 4.13 | 4.13 |
| 818.31 | 6.10 | 6.10 |
| 1253.51 | ||
| 1181.45 | ||
| 1103.42 |