Basic Information
ID: ALA5260629
Type: Binding
Description: Inhibition of human OATP2B1 expressed in Flp-In-CHO cells assessed as inhibition of OATP2B1 mediated DBF uptake using DBF as fluorescent substrate incubated for 2 mins by BCA assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Flp-In-CHO
Target: Solute carrier organic anion transporter family member 2B1(ALA1743124)
Document: ALA5257155
Inhibition of human OATP2B1 expressed in Flp-In-CHO cells assessed as inhibition of OATP2B1 mediated DBF uptake using DBF as fluorescent substrate incubated for 2 mins by BCA assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5260629
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.24 | 2.58 | 2.58 |
| 270.24 | 2.58 | 2.58 |
| 302.24 | 1.99 | 1.99 |
| 272.26 | 2.51 | 2.51 |
| 288.25 | 2.22 | 2.22 |
| 254.24 | 2.87 | 2.87 |
| 286.24 | 2.28 | 2.28 |
| 286.24 | 2.28 | 2.28 |
| 286.24 | 2.28 | 2.28 |
| 442.38 | 2.53 | 2.53 |
| 458.38 | 2.23 | 2.23 |
| 286.24 | 2.28 | 2.28 |
| 318.24 | 1.69 | 1.69 |
| 448.38 | 0.49 | 0.49 |
| 284.27 | 2.88 | 2.88 |
| 610.52 | -1.69 | -1.69 |
| 318.24 | 1.69 | 1.69 |
| 464.38 | -0.54 | -0.54 |
| 464.38 | -0.54 | -0.54 |
| 450.40 | -0.31 | -0.31 |
| 434.40 | -0.02 | -0.02 |
| 432.38 | 0.05 | 0.05 |
| 464.38 | 0.19 | 0.19 |
| 464.38 | -0.22 | -0.22 |