Basic Information
ID: ALA5261235
Type: Functional
Description: Antiviral activity against Hepatitis C virus subtype 1b infected in Huh-7 cells transfected with HCV subgenomic replicon for NS5B polymerase assessed as inhibition of viral replication measured upto 96 hrs in presence of 40% of human serum by luciferase reporter gene assay
Organism: Hepacivirus hominis
Strain: subtype 1b
Cell type: Huh-7
Activity Charts
Bioactivity
Activity Types for Assay ALA5261235
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.63 | 5.31 | 5.31 |
| 446.61 | 4.48 | 4.48 |
| 446.61 | 4.48 | 4.48 |
| 474.62 | 3.86 | 3.86 |
| 444.60 | 4.23 | 4.23 |
| 472.65 | 5.01 | 5.01 |
| 444.60 | 4.23 | 4.23 |
| 472.65 | 5.01 | 5.01 |
| 458.62 | 4.62 | 4.62 |
| 458.62 | 4.62 | 4.62 |