Basic Information
ID: ALA5263167
Type: Binding
Description: Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS addition and measured after 60 mins by TopCount NXT based scintillation analysis
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA5263167
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 292.45 | 2.80 | 2.80 |
| 295.85 | 4.17 | 4.17 |
| 436.68 | 5.87 | 5.87 |
| 436.68 | 5.87 | 5.87 |
| 450.71 | 6.26 | 6.26 |
| 450.71 | 6.26 | 6.26 |
| 465.68 | 4.21 | 4.21 |
| 493.74 | 4.97 | 4.97 |
| 416.61 | 5.98 | 5.98 |
| 450.71 | 6.12 | 6.12 |
| 466.71 | 5.23 | 5.23 |
| 492.75 | 6.08 | 6.08 |
| 422.66 | 5.48 | 5.48 |
| 450.71 | 6.26 | 6.26 |
| 450.71 | 6.26 | 6.26 |
| 452.68 | 4.84 | 4.84 |
| 464.74 | 6.65 | 6.65 |